Blood collection sites in animals pdf
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Total circulating blood volume is in the range of–ml/kg body weight. These guidelines are for normal, healthy adult animals Blood Collection Limits. Guidelines for safe blood withdrawal for laboratory mammals take into account the fact that each species has a different blood volume to body weight ratio measured in milliliters of blood to kilogram of body weight. Venipuncture, phlebotomy, or blood collection is a specific and important procedure for collecting samples from research animals. Terminal Blood Collection Terminal blood collection represents (i) exsanguination as a single process of blood removal to This article deals with the approved blood collection techniques for laboratory animals like rodents, lagomorphs and nonrodents I. Overview. Determining safe collection limits. Many research techniques require multiple lists possible blood collection sites for multiple species. Serial blood sampling limit vary by species, strain, and frequency of blood collection as outlined in Tablesand 3 The method of blood collection and volume collected can impact animal health and welfare. I. Overview. The ACUC limits one time survival blood collection to% of an animal’s blood volume in most circumstances. Guidelines for safe blood withdrawal for laboratory mammals take into account the fact that each species has a Guidelines. This column Various regulatory agencies and guidelines have restricted the use of animals and the techniques used for blood collection in laboratory animals. With provision of replacement fluids (% saline, Lactated Ringer’s solution) equaling the volume of blood removed, up Collecting Blood from Lab Animals Guidelines. Blood collection limits should be expressed as a proportion, or percentage, of an individual animal’s circulating blood volume (CBV) Phlebotomy (blood collection) is an important diagnostic tool for determining causes of morbidity and mortality and for collection of other research-relevant data. Repeated blood sample collection in mice, rats, hamsters, guinea pigs, small cats, and birds can be problematic because of their small body size older and obese animals compared to normal weight and young animals.