Diabetic neuropathy review article pdf
Rating: 4.6 / 5 (2212 votes)
Downloads: 34231
CLICK HERE TO DOWNLOAD
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes mellitus and is associated with increased mortality, lower-limb amputations and distressing Diabetic neuropathies are a heterogeneous group of disorders that include a wide range of abnormalities. Using vibratory perception threshold measurement,% had neuropathy, affecting% of known versus 7% of newly diagnosed patients. Retinopathy and proteinuria were associated with a doubling of likelihood of neuropathy Diabetes mellitus (DM) remains a public health problem, affecting million people worldwide. The effects of DPN on patient morbidity and quality of life are substantial; it predisposes to falls and superficial injuries, which can lead to infection and amputationIndividuals with diabetes and DPN are at higher risk of all-cause and This study included 1, previously known and newly detected diabetic patients. This review discusses the risk factors for DN, the main characteristics of the clinical forms of DN, the screening methods and the current therapeutic options Core Tip: This review elaborates on the current aspects regarding diabetic neuropathy (DN), especially issues pertaining to the treatments and current challenges in the management of DN with some suggested recommendations on strategies to slow down DN progression Abstract. Diabetic peripheral neuropathy (DPN) occurs in up to half of individuals with typeor typediabetes. They can be focal or diffuse, proximal or distal, affecting both peripheral and This review article aims to provide a comprehensive overview of the pathophysiology of diabetic neuropathy. [1,2,3] Moreover, the International Diabetes Federation estimates a global prevalence of million people by the year [4]Diabetic neuropathy (DN) is a frequent complication of diabetes mellitus (DM) with severe consequences as it progresses and influences all human body systems. DPN results from the distal-to-proximal loss of peripheral nerve function, This review article provides a comprehensive understand-ing of the pathophysiology of diabetic neuropathy, highlight-ing the mechanisms underlying nerve damage and the focus of this Review and will be referred to as diabetic peripheral neuropathy (DPN). The etiology of diabetic neuropathy will be discussed, including risk factors, predisposing conditions, and an overview of the complex interplay between hypergly-cemia, metabolic dysregulation, and nerve damage In the United States, about million people have DM and million new cases are diagnosed every year.