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Abstract. More. Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome characterized by widespread activation of coagulation leading to fibrin deposition in the vasculature, organ dysfunction, consumption of clotting factors and platelets, and life-threatening hemorrhage The PMIDDOI: /jx. Disseminated intravascular coagulation (DIC) is a syndrome characterized by the systemic activation of blood coagulation, which generates intravascular fibrin, DIC is a complicated acquired, systemic disorder of the body’s hemostatic process that involves a combination of hemorrhaging and microvascular coagulation. The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and Disseminated intravascular coagulation (DIC) is an acquired clinicobiological syndrome characterized by widespread activation of coagulation leading to fibrin deposition in the Disseminated intravascular coagulation (DIC) is a reflection of an underlying systemic disorder which affects the coagulation system, simultaneously resulting in pro-coagulant ISBNLegal deposit D///Introduction. Introduction. The International Society of Thrombosis and Haemostasis (ISTH) DIC subcommittee defines DIC as “an acquired syndrome characterized by intravascular activation of coagulation Abstract Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by widespread intravascular activation of coagulation that can be caused by infectious insults PDF ePub. Abstract. Disseminated intravascular coagulation (DIC) is a syndrome characterised by systemic intravascular activation of coagulation, leading to the widespread deposition of fibrin, with formation of widespread microvascular thrombosis Disseminated intravascular coagulation (DIC) can be defined as a widespread hypercoagulable state that can lead to both microvascular and macrovascular clotting and compromised blood flow, ultimately resulting in multiple organ dysfunction syndrome or MODS DIC is a complicated acquired, systemic disorder of the body’s hemostatic process that involves a combination of hemorrhaging and microvascular coagulation.